Lu, L. & Zhang, F. A deep tissue optical sensing. Nat. Nanotechnol. 17, 566–568 (2022).
Huang, J. et al. Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury. Nat. Mater. 18, 1133–1143 (2019).
Shuhendler, A. J. et al. Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing. Nat. Biotechnol. 32, 373–380 (2014).
Akemann, W. et al. Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins. Nat. Methods 7, 643–649 (2010).
Germain, R. N. et al. A decade of imaging cellular motility and interaction dynamics in the immune system. Science 336, 1676–1681 (2012).
Ellenbroek, S. I. J. & van Rheenen, J. Imaging hallmarks of cancer in living mice. Nat. Rev. Cancer 14, 406–418 (2014).
Harney, A. S. et al. Real-time imaging reveals local, transient vascular permeability, and tumor cell intravasation stimulated by TIE2hi macrophage–derived VEGFA. Cancer Discov. 5, 932–943 (2015).
Beura, L. K. et al. Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory. Nat. Immunol. 19, 173–182 (2018).
Damisah, E. C. et al. A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging. Nat. Neurosci. 20, 1023–1032 (2017).
Gonzales, A. L. et al. Contractile pericytes determine the direction of blood flow at capillary junctions. Proc. Natl Acad. Sci. USA 117, 27022–27033 (2020).
Hartmann, D. A. et al. Brain capillary pericytes exert a substantial but slow influence on blood flow. Nat. Neurosci. 24, 633–645 (2021).
Hofer, S. B. et al. Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex. Nat. Neurosci. 14, 1045–1052 (2011).
Knopfel, T. Genetically encoded optical indicators for the analysis of neuronal circuits. Nat. Rev. Neurosci. 13, 687–700 (2012).
Mehlenbacher, R. D. et al. Nanomaterials for in vivo imaging of mechanical forces and electrical fields. Nat. Rev. Mater. 3, 17080 (2018).
Hontani, Y. et al. Multicolor three-photon fluorescence imaging with single-wavelength excitation deep in mouse brain. Sci. Adv. 7, eabf3531 (2021).
Horton, N. G. et al. In vivo three-photon microscopy of subcortical structures within an intact mouse brain. Nat. Photon. 7, 205–209 (2013).
Liu, H. J. et al. In vivo deep-brain structural and hemodynamic multiphoton microscopy enabled by quantum dots. Nano Lett. 19, 5260–5265 (2019).
Xu, H. et al. Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex. Nat. Neurosci. 10, 549–551 (2007).
Hong, G. et al. Near-infrared fluorophores for biomedical imaging. Nat. Biomed. Eng. 1, 0010 (2017).
Bruns, O. T. et al. Next-generation in vivo optical imaging with short-wave infrared quantum dots. Nat. Biomed. Eng. 1, 0056 (2017).
Chang, B. et al. A phosphorescent probe for in vivo imaging in the second near-infrared window. Nat. Biomed. Eng. 6, 629–639 (2022).
Bandi, V. G. et al. Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines. Nat. Methods 19, 353–358 (2022).
Jia, Q. et al. Orthogonal near-infrared-II imaging enables spatially distinguishing tissues based on lanthanide-doped nanoprobes. Anal. Chem. 92, 14762–14768 (2020).
Ortgies, D. H. et al. Lifetime-encoded infrared-emitting nanoparticles for in vivo multiplexed imaging. ACS Nano 12, 4362–4368 (2018).
Fan, Y. et al. Lifetime-engineered NIR-II nanoparticles unlock multiplexed in vivo imaging. Nat. Nanotechnol. 13, 941–946 (2018).
Zhong, Y. et al. In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles. Nat. Biotechnol. 37, 1322–1331 (2019).
Cosco, E. D. et al. Shortwave infrared polymethine fluorophores matched to excitation lasers enable non-invasive, multicolour in vivo imaging in real time. Nat. Chem. 12, 1123–1130 (2020).
Cosco, E. D. et al. Bright chromenylium polymethine dyes enable fast, four-color in vivo imaging with shortwave infrared detection. J. Am. Chem. Soc. 143, 6836–6846 (2021).
Fan, Y. & Zhang, F. A new generation of NIR-II probes: lanthanide-based nanocrystals for bioimaging and biosensing. Adv. Opt. Mater. 7, 1801417 (2019).
Wang, F. & Liu, X. Upconversion multicolor fine-tuning: visible to near-infrared emission from lanthanide-doped NaYF4 nanoparticles. J. Am. Chem. Soc. 130, 5642–5643 (2008).
Zhong, Y. et al. Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm. Nat. Commun. 8, 737 (2017).
Suyver, J., Aebischer, A., García-Revilla, S., Gerner, P. & Güdel, H. Anomalous power dependence of sensitized upconversion luminescence. Phys. Rev. B 71, 125123 (2005).
Liu, Y. et al. Amplified stimulated emission in upconversion nanoparticles for super-resolution nanoscopy. Nature 543, 229–233 (2017).
Shi, R. & Mudring, A. V. Phonon-mediated nonradiative relaxation in Ln3+-doped luminescent nanocrystals. ACS Mater. Lett. 4, 1882–1903 (2022).
Quintanilla, M. et al. Cubic versus hexagonal—phase, size and morphology effects on the photoluminescence quantum yield of NaGdF4:Er3+/Yb3+ upconverting nanoparticles. Nanoscale 14, 1492–1504 (2022).
Shen, Z. et al. An artery-specific fluorescent dye for studying neurovascular coupling. Nat. Methods 9, 273–276 (2012).
Hill, R. A. et al. Regional blood flow in the normal and ischemic brain is controlled by arteriolar smooth muscle cell contractility and not by capillary pericytes. Neuron 87, 95–110 (2015).
Kolaczkowska, E. & Kubes, P. Neutrophil recruitment and function in health and inflammation. Nat. Rev. Immunol. 13, 159–175 (2013).
Kreisel, D. et al. In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation. Proc. Natl Acad. Sci. USA 107, 18073–18078 (2010).
Stark, K. et al. Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and ‘instruct’ them with pattern-recognition and motility programs. Nat. Immunol. 14, 41–51 (2013).
Ng, L. G. et al. Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events. J. Invest. Dermatol. 131, 2058–2068 (2011).
Lim, K. et al. In situ neutrophil efferocytosis shapes T cell immunity to influenza infection. Nat. Immunol. 21, 1046–1057 (2020).
Justicia, C. et al. Neutrophil infiltration increases matrix metalloproteinase-9 in the ischemic brain after occlusion/reperfusion of the middle cerebral artery in rats. J. Cereb. Blood Flow. Metab. 23, 1430–1440 (2003).
Schmid, M. C. et al. Integrin CD11b activation drives anti-tumor innate immunity. Nat. Commun. 9, 5379 (2018).
Li, M. et al. Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy. Nat. Commun. 11, 1126 (2020).
LaFleur, M. W. et al. PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity. Nat. Immunol. 20, 1335–1347 (2019).
Hyun, Y. M. et al. Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels. J. Exp. Med. 209, 1349–1362 (2012).
Lim, K. et al. Neutrophil trails guide influenza-specific CD8+ T cells in the airways. Science 349, aaa4352 (2015).
Hong, G. et al. Ultrafast fluorescence imaging in vivo with conjugated polymer fluorophores in the second near-infrared window. Nat. Commun. 5, 4206 (2014).
- SEO Powered Content & PR Distribution. Get Amplified Today.
- PlatoData.Network Vertical Generative Ai. Empower Yourself. Access Here.
- PlatoAiStream. Web3 Intelligence. Knowledge Amplified. Access Here.
- PlatoESG. Automotive / EVs, Carbon, CleanTech, Energy, Environment, Solar, Waste Management. Access Here.
- BlockOffsets. Modernizing Environmental Offset Ownership. Access Here.
- Source: https://www.nature.com/articles/s41565-023-01422-2